254. Measurement of Cerebral Vascular Permeability using Dynamic CT
نویسندگان
چکیده
منابع مشابه
Dynamic CT measurement of cerebral blood flow: a validation study.
BACKGROUND AND PURPOSE Our objective was to develop a method to correct for the effect of partial volume averaging (PVA) in the CT measurement of contrast enhancement in small arteries, and to validate a dynamic contrast-enhanced CT method for the measurement of regional cerebral blood flow (rCBF). METHODS Contrast-enhanced CT scans of tubes of known inner diameters were obtained to estimate ...
متن کاملPerfusion and vascular permeability: basic concepts and measurement in DCE-CT and DCE-MRI.
The microvascular network formed by the capillaries supplies the tissues and permits their function. It provides a considerable surface area for exchanges between blood and tissues. All pathological conditions cause changes in the microcirculation. These changes can be used as imaging biomarkers for the diagnosis of lesions and optimisation of treatment. Among the many imaging techniques develo...
متن کاملthe minimum percentage of triolein emulsion for studying cerebral vascular permeability with least brain edema
conclusion the minimum concentration of triolein emulsion required to increase vascular permeability adequately with minimal brain edema in a cat model was 0.5%. results the lesion hemispheres showed mild hyperintensity due to edema on t2-weighted images, and contrast enhancement on post-contrast t1-weighted images in cats of group 1-5. cers showed statistically significant differences between ...
متن کاملQuantitative cerebral blood flow measurement with dynamic perfusion CT using the vascular-pixel elimination method: comparison with H2(15)O positron emission tomography.
BACKGROUND AND PURPOSE Blood vessels are usually conspicuous on dynamic CT perfusion images. The presence of large vessels may lead to overestimation of the quantitative value of cerebral blood flow (CBF). We evaluated the efficacy of the vascular-pixel elimination (VPE) method in quantitative CT perfusion imaging, in comparison with positron emission tomography (PET). METHODS Five healthy vo...
متن کاملDelay correction for the assessment of blood-brain barrier permeability using first-pass dynamic perfusion CT.
SUMMARY Hemorrhagic transformation is a serious potential complication of ischemic stroke with damage to the BBB as one of the contributing mechanisms. BBB permeability measurements extracted from PCT by using the Patlak model can provide a valuable assessment of the extent of BBB damage. Unfortunately, Patlak assumptions require extended PCT acquisition, increasing the risk of motion artifacts...
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ژورنال
عنوان ژورنال: Japanese Journal of Radiological Technology
سال: 1990
ISSN: 0369-4305,1881-4883
DOI: 10.6009/jjrt.kj00003322378